Join our team

Building the AI operating system for genetic disease.

Probably Genetic is developing one of the most comprehensive data platforms for genetic disease, combining patient intelligence, genomic data, and machine learning to power research, diagnosis, and treatment at scale.

See open roles →

Backed by top investors

Y Combinator
Khosla Ventures
Threshold Ventures
TenOneTen Ventures
Recode Ventures
& more

Life at PG

We're a small, tight-knit team of wicked smart do-gooders fired up about helping patients find answers. Our work helps save lives. We build the critical infrastructure that drug developers, diagnostic labs, and 50+ patient advocacy organizations rely on to identify, diagnose, and treat genetic disease.

🧬

Powered by purpose

Severe, complex disease is one of the hardest problems in medicine. We're here because helping patients access diagnoses, trials, and treatments earlier is worth doing well.

🤖

Serious technical depth

LLMs, phenotyping algorithms, genomic sequencing pipelines, and population-scale data infrastructure, all purpose-built for genetic disease. The stack is genuinely interesting and the problems are unsolved.

Ship with velocity

Patients can wait years for a diagnosis. On our platform, they get answers in weeks. We bring that same urgency to how we ship, hire, and make decisions.

Our Values

Five key behaviors that guide how we make decisions, treat each other, and show up for the patients we serve.

01

We serve patients

Every algorithm we ship, every dataset we build, and every decision we make is ultimately in service of patients waiting for a diagnosis. That's the north star. We don't lose sight of it.

02

We create magic

We set a high bar for what's possible and push past it. Good enough isn't good enough when the people depending on us have spent years without answers.

03

We hustle

We move fast and prioritize ruthlessly. We ship, learn, and iterate because urgency isn't just a culture value here. It's a biological one.

04

We care

We show up for our teammates the same way we show up for patients, with empathy, generosity, and a genuine investment in each other's success.

05

We are radically candid

We say what we think, challenge ideas directly, and give feedback that actually helps people grow. Honest conversations make us better as a team and as a company.

What we offer

We take care of the people who take care of our patients.

❤️

Work that saves lives

Every model we train, every dataset we build, and every feature we ship moves us closer to a diagnosis for someone who's been waiting years for answers. The impact here is real.

📈

A stake in our success

Generous early-stage equity grants from day one. We're early, the upside is meaningful, and we want everyone on the team to share in what we create together.

🏙️

Hybrid, your way

Three days a week in our downtown SF office, two days wherever you do your best thinking. Collaboration when it counts, flexibility always.

🌴

Rest is part of the job

Flexible time off we genuinely encourage you to use. Rested people do better work. We mean it.

✈️

Work from anywhere

Four weeks a year to plug in from wherever inspires you — a different city, a different country, or your parents' kitchen. No questions asked.

🚀

Hack, retreat, repeat

Regular hackathons to push the limits of what's possible, and team retreats to step back, connect, and remember why we're all here.

Featured Openings

Senior Software Engineer

Help design and build our AI-enabled patient experience, genetic sequencing workflows, and the infrastructure behind a world-class patient intelligence platform.

Engineering San Francisco Full-time
View role →

Head of Engineering

Lead the engineering team building our patient intelligence platform: AI-driven phenotyping, genetic sequencing pipelines, and the systems that connect 200,000+ patients to diagnoses, trials, and treatments.

Engineering San Francisco Full-time
View role →

Senior Software Engineer, Data

Our founding Data Engineer. Build the data platform that powers genetic, phenotypic, and patient insights for drug developers and patient advocacy groups.

Engineering San Francisco Full-time
View role →

Don't see a perfect fit? We're always interested in hearing from exceptional people who care about this mission.